Calorie Restriction (CR) Diet


CR & Disease: Pancreatic Cancer Research

April 20, 2008

CR May Provide Some Protection Against Pancreatic Cancer, Based On Animal Studies

Following are excerpts and references from animal studies of the effects of CR on pancreatic cancer. In all cases the original paper should be read for a full understanding of what was being studied and what could be concluded.

Human Studies (None Available)

Animal Studies

  1. Title: "Calorie Restricted Diet Prevents Pancreatic Inflammation and Cancer"

    News Release, April 14, 2008, The University of Texas MD Anderson Cancer Center; Stephen D. Hursting, Laura Lashinger, Susan Fischer, Lauren Malone, Elizabeth Daniels, Nicole Smith, Susan Perkins, Amy Pavone, and Jennifer Colby

    News Release, April 14, 2008

    "Our findings indicate that calorie restriction hinders development of pancreatic cancer, which could have implications for prevention and treatment of pancreatic tumors caused by chronic inflammation and obesity."

    "While calorie restriction has been shown to have an anti-cancer effect in multiple species and for a variety of tumor types, its impact had not been well-studied in a model of pancreatic cancer. Pancreatic cancer is the fourth leading cause of cancer death and remains mostly intractable to existing treatments."

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