CR May Provide Some Protection Against Diabetes, Based On Animal Studies
Following are excerpts and references from animal studies of the effects of CR on diabetes. In all cases the original paper should be read for a full understanding of what was being studied and what could be concluded.
Human Studies (None Available)
Animal Studies - Primate
Title: "Caloric Restriction Delays Disease Onset and Mortality in Rhesus Monkeys"
Ricki J. Colman, Rozalyn M. Anderson, Sterling C. Johnson, Erik K. Kastman,
Kristopher J. Kosmatka, T. Mark Beasley, David B. Allison, Christina Cruzen,
Heather A. Simmons, Joseph W. Kemnitz, and Richard Weindruch
Science 10 July 2009: 201-204
"Improvements in metabolic function conferred by CR, specifically insulin
sensitivity, have been consistent and striking (9, 13). We found that
improved glucose homeostasis was maintained and that diabetes was prevented
by CR. Of the initial 38 control animals, 5 progressed to diabetes and an
additional 11 were classed as pre-diabetic. In contrast, all animals on CR
(even those with compromised metabolic function at baseline) showed no
impairment of glucose homeostasis (Fig. 3A). These data are consistent with
CR providing long-term health benefits in protection against diabetes."